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Dr. Timothy L. Vollmer
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Barrow Neurological Institute
St. Joseph's Hospital and Medical Center
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Timothy L. Vollmer M.D.
Director, Barrow NeuroImmunology Program
Barrow Neurological Institute
St. Joseph's Hospital and Medical Center


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September 03, 2005

 

STUDY:Factors leading patients to discontinue multiple sclerosis therapies

RESULTS: There was no significant difference between the percentages of patients who discontinued and did not restart treatment with the products (interferon beta-1b, 41%; intramuscular interferon beta-1a, 34%; and glatiramer acetate, 28%). Four main reasons for medication discontinuation emerged: adverse effects (52%), physician-documented disease progression (40%), patient perception of drug ineffectiveness (20%), and cost (4%). No statistical differences were identified among the three agents for any of the reasons for discontinuation." CONCLUSION: Patient education on adverse effects and realistic patient expectations may be potential areas of study to improve discontinuation percentages with these agents.
MORE...Entrez PubMed