Cytokine-Suppressor Gene Protects Mice From MS-Type Damage:
[Abstract: Journal of Neuroimmunology] "The expression of a gene, known as suppressor of cytokine signaling 1 gene (SOCS1), protects oligodendrocytes from the deleterious effects of interferon gamma. This, researchers report in the May 10th issue of the Journal of Neuroscience, may block the progression of multiple sclerosis (MS)...."Our results suggest that stem cells engineered to be resistant to the harmful cytokines present in the extracellular milieu of the breached CNS of MS patients would stand a better chance of surviving and accomplishing remyelination," Dr. Popko concluded."