"Among newly diagnosed multiple sclerosis (MS) patients, fatigue and depression significantly affect quality of life, but cognitive dysfunction does not, researchers reported here on September 29th at the 21st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)....In a third of the subjects fatigue and sensory disturbances were the two symptoms most severely diminishing quality-of-life. Difficulties in walking (17%) was third....."We found that cognitive deficits, although they are present, don't have an impact on quality-of-life. But fatigue and depression have an impact on quality-of-life," ...The authors concluded, "Both cognitive dysfunctions and fatigue are frequently demonstrable in newly diagnosed MS patients. Fatigue and depression, but not cognition, have negative consequences for quality of life already at time of diagnosis. Mild cognitive impairment at time of diagnosis could be a reason for the missing association between cognition and quality of life. On the other hand, the impairment often affects only one cognitive function, so the other functions can compensate deficits in daily demands." MORE